Major Drug Makers
Often referred to as "Big Pharma," this sector consists of large, diverse corporations that research, manufacture, and market proprietary brand-name medications globally.
Why it exists
Major drug makers exist to commercialize therapies at global scale after discovery.
Why it’s necessary
They provide the manufacturing, regulatory, distribution, and marketing muscle required to turn science into mass-access medicine.
Key components
Global manufacturing networks
Sales and medical affairs organizations
Patent portfolios
Post-approval surveillance systems
How to evaluate businesses
Patent life, pipeline replenishment, pricing power, geographic exposure, and capital allocation discipline define winners. Watch revenue cliffs from patent expiration.
How the industry could be improved
Smarter acquisition strategies, real-world pricing tied to outcomes, AI-driven trial design, and faster post-approval access globally.


